Ulthera Prime — The Latest Model
What is Ulthera Prime? For those familiar with skin-tightening treatments, the Ulthera device needs little introduction. It’s a leading non-surgical skin-lifting innovation widely used in aesthetic clinics. In 2025, the brand introduced Ulthera Prime — also known as Ultherapy Prime — the first major new release in 15 years, sparking even greater interest among patients and practitioners.
This article explores the benefits and standout features of Ulthera Prime compared to the previous generation — covering its technology, results, and pricing.
Table of Content : Ulthera Prime
What Is Ulthera Prime?
Ulthera Prime is the latest skin-tightening technology, developed from Ulthera SPT by Merz Aesthetics, USA. Globally recognized in dermatology, it is classified as a non-invasive treatment — meaning no surgery is required — yet it effectively addresses skin laxity and visible wrinkles.
How Ulthera Prime Works
Ulthera Prime uses Microfocused Ultrasound with Visualization (MFU-V) technology to deliver focused ultrasound energy to the SMAS layer — the same layer targeted during surgical facelifts. This process causes the skin to contract and lift immediately, while also stimulating the production of new collagen and elastin, resulting in firmer, more elastic skin over time.
Key Features of Ulthera Prime
One of Ulthera Prime’s main advantages is its enhanced precision in visualizing skin layers. The device features a Full HD display that is 35% larger than the previous model, allowing doctors to clearly see the skin’s structure during treatment and adjust energy levels according to each patient’s specific skin concerns.
How Is Ulthera Prime Different from the Previous Model?
Ulthera Prime has been upgraded in multiple aspects compared to the earlier Ulthera SPT model, improving both performance and ease of use for practitioners. These advancements not only enhance treatment outcomes but also provide a more comfortable and satisfying experience for patients.
Faster Processing Speed
Ulthera Prime processes 20% faster than the previous model, reducing overall treatment time and minimizing patient discomfort during the procedure.
Full HD Display
The new display offers 35% higher resolution and a larger screen size, combined with advanced visualization technology that provides real-time imaging of skin layers. This allows doctors to target treatment areas with greater precision, adjusting energy delivery to match each individual’s concerns.
Greater Treatment Flexibility
With MFU-V technology and newly added features, Ulthera Prime offers improved customization, enabling doctors to tailor treatments more precisely to each patient’s unique skin condition.
Modern, Compact Design
Ulthera Prime features a sleeker, more compact design, making it easier and more convenient for practitioners to operate.
Comparing Ulthera Prime with Other Skin-Tightening Technologies
Here’s how Ulthera Prime compares to other popular skin-tightening devices:
HIFU
HIFU (High-Intensity Focused Ultrasound) uses high-frequency ultrasound waves similar to Ulthera Prime. However, the key difference is that HIFU does not have a visualization system, meaning the doctor cannot see the skin layers during treatment. This may result in less precision, and optimal results depend heavily on the practitioner’s skill and experience. Currently, the most popular HIFU devices are HIFU Ultraformer III and Ultraformer MPT.
Thermage
Thermage uses radiofrequency (RF) energy to stimulate collagen production and tighten the skin. It can target the dermis and subcutaneous fat layers, but does not reach the SMAS layer like Ulthera Prime. Additionally, Ulthera Prime offers real-time skin visualization, allowing for more precise and consistent results.
Morpheus8
Morpheus8 is an RF-based device with microneedle-like pins on the handpiece — unlike other lifting devices, which have smooth applicator tips. When applied to the skin, these needles deliver energy to multiple layers, from the superficial skin down to the dermis. It is particularly effective for improving skin texture, reducing wrinkles, and creating a smoother, plumper appearance.
Laser
Laser treatments focus on addressing surface-level skin concerns such as redness, dark spots, and uneven pigmentation. They do not penetrate to the SMAS layer like Ulthera Prime, making them better suited for patients with superficial skin issues rather than deeper skin laxity.
The most important factor in choosing a device is understanding your specific concerns and goals. Selecting the right treatment ensures targeted correction, optimal results, and the best value for your investment.
What Can Ulthera Prime Treat?
Ulthera Prime is a versatile technology designed to address various skin concerns, particularly skin laxity and wrinkles.
- Lift and tighten the face and neck: Reduces sagging in the cheeks, jawline, and neck for a more defined facial contour and firmer skin.
- Lift brows and reduce under-eye bags: Brightens the eyes and minimizes wrinkles around the eye area.
- Reduce double chin and tighten under the chin: Creates a slimmer, more contoured neckline.
- Stimulate collagen and elastin production: Slows the formation of wrinkles and helps maintain youthful-looking skin.
Who Is Ulthera Prime Suitable For?
- Individuals seeking non-surgical facial lifting
- Those with sagging or loose skin
- People who want to contour and define the jawline
- Individuals with fine lines, such as nasolabial folds or under-eye wrinkles
- Those with drooping brows, outer eye corners, or eyelids
- Individuals wanting to restore firmness and elasticity to aging facial skin
- Those looking to smooth and tighten the neck area
Which Areas Can Ulthera Prime Treat?
Ulthera Prime can be used to lift and tighten multiple areas of the body, especially those prone to sagging:
- Face: Forehead, brows, around the eyes, cheeks, jawline
- Neck: Reduces double chin and tightens skin
- Other areas: Abdomen, upper arms, thighs
How Many Lines Does Each Ulthera Prime Treatment Area Require?
- Ulthera Prime around the eyes: 200 lines
- Ulthera Prime cheeks: 300 lines
- Ulthera Prime cheeks + double chin: 500 lines
- Ulthera Prime full face: 700 lines
- Ulthera Prime full face + neck: 1,000 lines
The number of lines required varies depending on the patient’s skin condition, problem areas, and the size of the treatment zone. The doctor will assess and recommend the appropriate line count on a case-by-case basis.
Consult a qualified doctor before undergoing Ulthera Prime.
Ulthera Prime Procedure Steps
- Consultation with the doctor — The doctor will analyze your skin concerns and create a personalized treatment plan tailored to your needs.
- Preparing the skin — The treatment area will be cleansed, and a topical anesthetic will be applied to minimize discomfort.
- Performing the procedure — The doctor will use the Ulthera Prime device to deliver energy precisely to the targeted skin layers according to the treatment plan. This step typically takes about 30–60 minutes.
- Post-treatment care — You can return to your normal daily activities immediately, with no downtime required.
Does Ulthera Prime Hurt?
Ulthera Prime is generally tolerable in terms of discomfort. Patients usually feel a warm, tingling sensation in the treated areas, and a topical anesthetic is applied beforehand to help reduce it.
Patients who have experienced both Ulthera SPT and Ulthera Prime often report that Ulthera Prime is less painful, as the treatment time is shorter.
How Soon Will You See Results from Ulthera Prime?
After the treatment, patients can expect to see about 20–30% of the final result immediately, as the SMAS layer is lifted through the contraction of collagen and elastin fibers beneath the skin, making the skin appear firmer.
The most noticeable improvement occurs over the next 2–3 months, during which time new collagen production reaches its peak, resulting in tighter, more lifted, and youthful-looking skin.
Patients with severe skin laxity or deep wrinkles may take slightly longer to see the full effect, but overall, Ulthera Prime delivers fast, satisfying, and long-lasting results.
A clinical study on patients who underwent Ulthera treatment on one side of the face found that collagen production on the treated side increased by an average of 1.4 times (42%) compared to the untreated side.
How Long Do Ulthera Prime Results Last?
The results from Ulthera Prime typically last 1–2 years, depending on age, skin condition, lifestyle habits, and post-treatment care.
- Age and skin condition: Younger patients or those with naturally elastic skin tend to maintain results longer than older individuals.
- Lifestyle habits: Protecting the skin from direct sun exposure, eating a healthy diet, and avoiding smoking can help extend results.
- Skincare routine: Using suitable skincare products, such as collagen-based creams or hydrating serums, helps maintain firmness for longer.
For those who want to maintain their skin-tightening results, it is recommended to repeat Ulthera Prime once a year to preserve its effectiveness.
Possible Side Effects After Ulthera Prime
Ulthera Prime is considered very safe and is approved by both the US FDA and Thailand’s FDA. However, in some cases, mild side effects may occur, such as:
- Temporary swelling or redness from the heat energy delivered into the skin
- Mild warmth or tingling in the treated area
- Increased skin sensitivity to touch for the first 1–2 days
These side effects are normal and do not cause long-term skin damage. If symptoms are severe or persist longer than expected, patients should consult a doctor immediately.
How Does Ulthera Prime Compare to Other Devices?
Ulthera Prime VS Ulthera
Ulthera, the original skin-lifting technology, uses focused ultrasound energy to target deep skin layers for lifting. Ulthera Prime, the latest model, offers significant upgrades in performance, precision, and treatment results.
Ulthera Prime VS Ultraformer MPT
Ulthera Prime has a larger focal energy point, which contributes to longer-lasting results. It also features a real-time display showing the depth of the treatment area, including the SMAS layer. This allows both the doctor and patient to see detailed imaging during the procedure, improving accuracy. Both devices can be combined in a treatment plan for enhanced lifting results.
Ulthera Prime VS Ulthera SPT
The main differences between Ulthera Prime and Ulthera SPT are the redesigned, larger display and improved energy stability in Ulthera Prime. Both devices deliver excellent lifting results. Watch the video below for a detailed explanation.
Ulthera Prime VS Thermage
For skin tightening, Ulthera Prime targets the SMAS layer and also stimulates collagen production, helping reduce fine lines on the surface. However, for patients with excess facial fat, fullness, double chin, severe sagging, or collagen loss, Thermage may be more suitable due to its strengths in tightening while also reducing fat.
How Much Does Ulthera Prime Cost?
The cost of Ulthera Prime varies depending on the treatment area and the number of lines used. Generally, prices start at 25,000–30,000 THB and increase with the number of lines required. Larger treatment areas — such as thighs, upper arms, or abdomen — typically cost more than facial treatments.
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How to Choose the Right Clinic for Ulthera Prime
When choosing a clinic for Ulthera Prime, avoid making decisions based solely on the lowest price, as this could mean the device is counterfeit — leading to poor results or potential side effects. For safe and effective treatment, check the following before deciding where to get Ulthera Prime:
- Clinic certification: Verify that the clinic meets quality standards and that the Ulthera Prime device is genuine, approved by both the US FDA and Thailand’s FDA.
- Experienced doctors: Choose a clinic with full-time doctors who have expertise in performing Ulthera Prime.
- Verified patient reviews: Reading testimonials from real patients helps evaluate the clinic’s quality and credibility.
Clinic environment and equipment: Ensure the clinic is clean, safe, and equipped with modern, up-to-date technology.
Ultherapy Prime Before-and-After Reviews
Post-Treatment Care After Ulthera Prime
To maximize the effectiveness and longevity of Ulthera Prime results, follow these aftercare guidelines during the first two weeks:
- Avoid pressing, massaging, or rubbing the treated area forcefully.
- Refrain from squeezing or vigorous facial rubbing.
- You may apply makeup, skincare creams, and moisturizers as usual.
- Avoid exfoliating products such as AHA, BHA, or Retinol.
- Apply sunscreen with SPF 50+ to protect the skin from UV damage.
- Avoid heat-based activities such as steam, sauna, or intense exercise.
- Avoid all deep-penetrating heat-based laser treatments for one month.
Restrictions After Ulthera Prime
There are no strict restrictions after Ulthera Prime, but it’s important to follow the doctor’s instructions and the aftercare guidelines mentioned above.
How Many Days Until Ulthera Prime Results Settle?
Swelling and redness typically subside within 1–2 days after the procedure. Results become more noticeable over the next 2–3 months as collagen and elastin production in the deeper layers of the skin reaches its peak.
Summary — Why Choose Ulthera Prime
- Ulthera Prime is an advanced and highly effective skin-tightening innovation.
- It corrects skin laxity and wrinkles without surgery or downtime.
- Powered by MFU-V technology, it delivers energy precisely to the SMAS layer — the same layer targeted in surgical facelifts.
- It provides precise, targeted lifting with results lasting up to 1–2 years.
For those seeking skin lifting and facial contouring, Ulthera Prime is an excellent choice — delivering safe, effective results when performed by an experienced doctor in a certified clinic.
Reference
- https://ultherapy.com/
- https://ultherapy.com/physicians-the-gold-standard
- https://ultherapy.com/physicians/optimized-neocollagenesis
- Fabi SG, Joseph J, Sevi J, Green JB, Peterson JD. Optimizing patient outcomes by customizing treatment with microfocused ultrasound with visualization: gold standard consensus guidelines from an expert panel. J Drugs Dermatol. 2019;18(5):426-432.
- Park JY, et al. Customized Treatment Using Microfocused Ultrasound with Visualization for Optimized Patient Outcomes: A Review of Skintightening Energy Technologies and a Pan-Asian Adaptation of the Expert Panel’s Gold Standard Consensus. J Clin Aesthet Dermatol. 2021;14(5):E70-E79.
- Whitney ZB, Zito PM. Anatomy, skin, superficial musculoaponeurotic system (SMAS), fascia. In: StatPearls. Treasure Island, FL: StatPearls Publishing; 2019. https://www.ncbi.nlm.nih.gov/books/NBK519014/. Updated October 27, 2018. Accessed December 9, 2019
- Suh DH, Choi JH, Lee SJ, Jeong KH, Song KY, Shin MK. Comparative histometric analysis of the effects of high-intensity focused ultrasound and radiofrequency on skin. J Cosmet Laser Ther. 2015;17(5):230-236.
- Fabi SG, Massaki A, Eimpunth S, Pogoda J, Goldman MP. Evaluation of microfocused ultrasound with visualization for lifting, tightening, and wrinkle reduction of the décolletage. J Am Acad Dermatol. 2013;69(6):965-971.
- Werschler WP, Werschler PS. Longterm efficacy of micro-focused ultrasound with visualization for lifting and tightening lax facial and neck skin using a customized vectoring treatment method. J Clin Aesthet Dermatol. 2016;9(2):27-33.
- Pavicic T, Ballard JR, Bykovskaya T, et al. Microfocused ultrasound with visualization: Consensus on safety and review of energy-based devices. J Cosmet Dermatol. 2021.
- White WM, Makin IR, Barthe PG, Slayton MN, Gliklich RE. Selective creation of thermal injury zones in the superficial musculoaponeurotic system using intense ultrasound therapy: a new target for noninvasive facial rejuvenation. Arch Facial Plast Surg. 2007;9(1):22-29.
- Sasaki G, Grossman J, Fabi SG, et al. Stimulation of Collagen Synthesis in Human Skin Following Microfocused Ultrasound Therapy. Presented at the ASDS 2018 Annual Meeting.
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