Pico Laser: A One-Stop Solution for Multiple Skin Concerns

Pico Laser is an advanced laser technology designed to address various pigmentation issues such as melasma, freckles, dark spots, acne marks, and acne scars. It works by targeting pigment particles in the skin at an ultra-fast speed, measured in picoseconds (one trillionth of a second). The energy precisely breaks down pigmentation without harming the surrounding tissue.
Table of Content : Pico Laser
What Is Pico Laser and Why Do Doctors Recommend It?
Pico Laser was specifically developed to treat pigment-related skin concerns, including melasma, freckles, dark spots, acne marks, acne scars, and even tattoos. It delivers high-intensity light pulses in an extremely short duration—picoseconds—making it thousands of times faster than traditional nanosecond lasers.
When Pico Laser targets pigment, it shatters it into ultra-fine particles that the body can naturally eliminate. Because this energy is not converted into heat, there’s less risk of burns, hyperpigmentation, or peeling. Additionally, it can stimulate collagen beneath the skin, leading to smoother, brighter skin.

How Does Pico Laser Work?
Pico Laser comes with various wavelengths—532, 755, and 1064 nanometers—each designed for different pigment depths:
- 532 nm: Ideal for superficial pigmentation like sunspots and freckles
- 755 nm: Effective for deeper melasma and green-blue tattoo ink
- 1064 nm: Targets deep pigmentation such as deep melasma, dark tattoo ink, and post-inflammatory hyperpigmentation
When energy is delivered, it works through two primary mechanisms:
- Targeted Photoacoustic Effect – Shattering Melanin Precisely
- The laser energy specifically targets melanin pigments responsible for skin issues such as melasma, freckles, and acne spots.
- The pigment particles are broken into dust-like fragments that are then gradually removed by the body’s natural processes.
- This precise targeting prevents burns and minimizes scabbing since the treatment doesn’t rely on heat.
- Laser-Induced Optical Breakdown (LIOB) – Collagen Stimulation
- When laser energy penetrates the dermis (middle skin layer), it creates microscopic vacuoles called LIOB (Laser Induced Optical Breakdown).
- These micro-injuries signal the body to produce new collagen for natural skin repair.
- The result is smoother skin, shallower acne scars, and tightened pores—all without damaging the outermost layer (epidermis).

Summary of Pico Laser Mechanism
- Delivers energy through mechanical impact, not heat
- Breaks down pigment particles for natural elimination by the body
- Minimizes the risk of peeling and post-treatment dark spots, or burning
- Stimulates deep collagen without affecting the skin’s surface
Advantages of Pico Laser Over Traditional Lasers
Today, Pico Laser is as popular as injectable procedures like fillers, botulinum toxin (Botox), and skin-tightening devices. Here’s why:
- Ultra-Fine Pigment Breakdown : Using mechanical shockwaves (photoacoustic effect), Pico Laser shatters pigment more finely than nanosecond lasers. This leads to faster results and reduces the chance of pigment recurrence.
- No Heat Accumulation, No Tissue Damage : Unlike older lasers that use thermal energy, Pico Laser does not generate heat, thus minimizing the risk of burns and skin peeling.
- Low Risk of Post-Inflammatory Hyperpigmentation (PIH) : Pico Laser’s heat-free technology lowers the chance of developing PIH or redness after treatment.
- Minimal Downtime : After Pico Laser treatment, the skin may appear slightly pink or mildly flaky, but patients can return to their regular activities immediately.
- Stimulates Collagen Production : By targeting deeper skin layers, Pico Laser helps improve acne scars, tighten pores, and enhance skin clarity and smoothness.
- Safe for All Skin Types : Since it doesn’t heat or peel the outer skin layer, Pico Laser is suitable even for individuals with sensitive skin or those who experienced side effects from other laser treatments.
- Treats Multiple Skin Concerns : Pico Laser addresses melasma, freckles, dark spots, acne marks, acne scars, enlarged pores, tattoos, and dull skin—all with one device.
- Immediate Results With Continued Improvements : For mild pigment concerns, visible improvement may appear after just one session. For deeper melasma or scars, multiple sessions are recommended for optimal outcomes.
Who Is a Good Candidate for Pico Laser?
Pico Laser is ideal for individuals with pigment-related skin issues, including:
- Melasma, Freckles, Sun-Induced Dark Spots : Pico Laser precisely targets pigment without damaging the surrounding skin, making it ideal for sensitive skin or those prone to post-laser dark marks. Deep melasma may require several sessions for visible improvement.
- Acne Marks That Fade Slowly : For acne that has healed but left behind dark spots (PIH) lasting for months or years, Pico Laser can accelerate fading without thinning the skin.
- Enlarged Pores and Uneven Texture : As collagen levels decrease with age, skin may appear dull and saggy. Pico Laser helps regenerate collagen, improving elasticity and texture.
- Shallow to Moderate Acne Scars : Mild to moderate acne scars—such as boxcar or rolling scars—respond well to Pico Laser, which stimulates natural skin repair. For deeper Ice Pick scars, doctors may recommend combining the treatment with subcision or filler injections.
- Tattoo and Birthmark Removal : Pico Laser breaks down tattoo pigments more effectively than older lasers, especially black, blue, and green inks, while minimizing scarring and reducing required sessions.
- Dull Skin from Sun Exposure or Pollution : For skin that looks dull or uneven due to accumulated sun damage or pollution, Pico Laser gently resurfaces pigment without peeling, restoring a radiant look.
- Previous Laser Treatments Were Ineffective or Caused Side Effects : If treatments like Q-Switched or IPL caused darkening or were ineffective, Pico Laser is a safer choice thanks to its heat-free precision targeting.
- Limited Time, No Downtime Needed : Ideal for individuals with busy schedules—Pico Laser allows an immediate return to daily routines. Regular application of moisturizer and sunscreen is recommended to maintain results.
What Can Pico Laser Treat?
Pico Laser is a versatile device that breaks down pigment while simultaneously stimulating collagen.

- Melasma, Freckles, Dark Spots
- Melasma: Targets melanin precisely without affecting the surrounding skin
- Freckles: Effective on both superficial and deeper UV-induced freckles
- Dark Spots: Treats pigmentation from acne, sun exposure, age, or hormones without peeling
- Acne Marks – Dark and Red Spots (PIH/PIE)
- PIH (Post-inflammatory Hyperpigmentation): Pico Laser fades these dark spots without thinning the skin
- PIE (Post-inflammatory Erythema): Low-energy Pico Toning reduces red acne marks effectively
- Dull Skin and Uneven Tone
Toning Mode disperses energy evenly across the face, brightening skin tone without peeling. Ideal for those with sun damage, uneven complexion, or previous laser-induced patchiness.
- Enlarged Pores and Rough Texture
Pico Laser penetrates the dermis to stimulate collagen without damaging the surface. Over 3–5 sessions, the skin becomes smoother and pores tighter.
- Mild to Moderate Acne Scars
Fractional Pico Laser delivers grid-like beams into the dermis to stimulate skin regeneration from within. Shallow acne scars (boxcar, rolling) gradually improve with consistent sessions.
- Tattoo and Birthmark Removal
Pico Laser efficiently breaks down pigment-rich tattoos and birthmarks in colors such as black, blue, green, and red. It requires fewer sessions than older lasers and carries a lower risk of scarring.
- Rejuvenation for Youthful-Looking Skin
With Rejuvenation Mode, Pico Laser promotes collagen and elastin renewal, improving skin firmness and radiance—great for addressing early fine lines without downtime.
- Oil Control and Clogged Pores
Gentle Pico Laser sessions can help regulate sebum (oil) production, ideal for chronic clogged pores, especially on the T-zone, chin, and jawline.


(Dr. Suranart Deesuwan, License ว.46313)
Skin Evaluation at V Square Clinic
Which Areas Can Be Treated with Pico Laser?

Pico Laser is not limited to facial treatments. It can also be used to treat pigmentation and rejuvenate skin on various parts of the body, depending on the individual’s skin condition, concern, and energy settings.
Generally, treatment areas are divided into two groups: common facial zones and treatable body areas.
Common facial zones
- Cheeks: The cheeks are often thin-skinned and directly exposed to sunlight, making them prone to melasma, freckles, dark spots, and acne marks. Pico Laser can effectively treat these issues without burning or peeling the skin.
- Forehead: This area commonly presents with acne marks or scattered dark spots. Low-energy Pico Toning is used here to even out skin tone gently.
- Chin: The chin often suffers from inflammatory acne, dark marks, and mild scarring. For shallow acne scars, the Pico Laser Fractional mode can help stimulate collagen production effectively.
- Nose: Common issues include acne marks, redness, and enlarged pores. Treatment requires high precision, so the doctor will adjust the laser energy based on skin thickness.
- Under-eye area: Dark circles from allergies or friction (rubbing) may improve with gentle Pico Laser sessions.
Treatable body areas
- Back of hands, arms, legs, inner elbows/knees: These areas are commonly affected by sun-induced freckles or dark spots. As the skin here can tolerate more energy than the face, higher energy levels may be applied.
- Underarms, inner thighs, bikini line: For pigmentation caused by friction, shaving, or waxing, Pico Laser can be used with low energy to fade darkened skin.
- Back, chest, shoulders: Ideal for post-acne dark spots or accumulated pigmentation. Due to the large surface area, multiple shots may be needed per session.
- Tattoos (any location): Whether on the arm, chest, back, legs, or ankles, Pico Laser can precisely target tattoo ink without causing raised scars.

Before treatment, the doctor will assess the individual’s skin condition and customize the treatment plan. Some areas like the under-eye, around the mouth, or skin folds have thinner skin, so technique and energy levels need to be carefully adjusted.
What Pico Laser Brands Are Available and Which One Should You Choose?
Currently, there are several Pico Laser machines imported from different countries. Each offers unique advantages based on technology and treatment focus:
| Machine | Country | Best for |
|---|---|---|
| PicoSure Pro | USA | Deep melasma, freckles, dark spots, acne marks, redness, enlarged pores, and acne scars |
| PicoPlus | Korea | Melasma, freckles, dark spots, acne redness, acne scars, tattoo removal |
| PicoWay | USA | Acne marks, scars, enlarged pores, melasma, freckles, dull skin |
| Discovery Pico | Italy | Acne marks, scars, keloid scars, tattoos and birthmark removal |
| Enlighten | USA | Acne scars, acne marks, acne, melasma, freckles, dark spots, enlarged pores |
At V Square Clinic, we primarily use two machines:
PicoSure Pro – Cynosure (USA)
PicoSure Pro Highlights
- Provides a comprehensive solution for various skin problems
- Reduces deep melasma, freckles, and dark spots – noticeable after one session
- Fades acne marks, redness, and dark spots
- Improves overall skin tone and radiance
- Minimizes pores and refines skin texture
- Stimulates collagen and elastin production

Pico Plus – Lutronic (Korea)
Pico Plus Highlights
- Delivers treatment with minimal bleeding, little to no downtime
- Reduces pigmentation, melasma, freckles, and dark spots
- Improves overall skin smoothness and brightness

How to Prepare Before Pico Laser Treatment
- Refrain from using Retin-A, AHA, and BHA at least 3–5 days before treatment
- Avoid direct sun exposure for one week prior to treatment
- Treat any active acne or inflammation before scheduling the session
- Inform the doctor if there is a personal history of keloid scarring
Pico Laser Procedure Steps

- The doctor evaluates the patient’s skin condition, identifying the underlying concerns.
- Pre-treatment preparation
- The skin is thoroughly cleansed.
- A numbing cream is applied and left on for 30–45 minutes to minimize discomfort.
- Protective goggles are also provided to shield the eyes during the procedure.
- The doctor performs Pico Laser treatment on the targeted areas.
- The doctor provides personalized aftercare instructions and schedules a follow-up appointment if necessary.
The full procedure typically takes around 30 minutes, depending on the size of the treatment area and the complexity of the skin concerns.
Post-Treatment Care for Pico Laser
- Avoid heat, direct sunlight, outdoor activities, and saunas for 1–2 weeks
- Apply sunscreen with SPF 50 PA+++ daily
- Use moisturizer to maintain skin hydration
- Avoid scrubbing, exfoliation, or irritating skincare products (e.g., AHA, BHA, Vitamin C, retinol)
- Wash the face with water only on the first day; afterward, normal skincare and makeup can be resumed
- Follow any prescribed medication exactly as directed
Does Pico Laser Hurt? How Many Sessions Are Needed?
During the procedure, patients may experience a light snapping sensation, mild warmth, or a slight sting. While results vary by individual, most patients see visible improvement after 3 to 5 sessions or more. The number of sessions required will depend on the severity of the concern, and the doctor will adjust the treatment plan based on the skin’s response over time.
Pico Laser Review at V Square Clinic



Melasma and PIH (Post–Inflammatory Hyperpigmentation)
How Much Does Pico Laser Cost?
Pico Laser treatments typically start from around 3,000–10,000 THB per session. Prices may vary by clinic depending on the Pico Laser brand used, treatment area (full face vs. targeted spots), the doctor’s experience, and ongoing clinic promotions.
Interested in doing Pico Laser at V Square Clinic?
Click to view our latest promotions.

Where Is the Best Place to Get Pico Laser Treatment?
- Trusted and reputable clinic: Choose a clinic known for delivering real results with professional service. Look for a clean, hygienic, and comfortable environment.
- Experienced doctors with laser expertise: Look for doctors who can provide a thorough consultation and have strong experience using Pico Laser devices to accurately and effectively target skin concerns.
- Certified laser machines: Make sure the clinic uses authentic FDA-approved Pico Laser machines.
- Variety of laser programs available: Choose a clinic that offers multiple types of Pico Laser programs (e.g., PicoSure Pro + Pico Plus) and can treat a wider range of skin concerns more comprehensively.
- Reasonable pricing—not too cheap or too expensive: Avoid clinics with unusually low prices, as this may indicate the use of uncertified or counterfeit equipment.
- Convenient online appointment system: Use clinics with a reliable online appointment system to minimize wait times and ensure timely service.
Why Choose V Square Clinic for Pico Laser?
- Treatments are performed by highly experienced doctors who specialize in laser procedures
- Personalized treatment plans designed for optimal results
- Facial analysis with Isemeco skin scanning technology for in-depth assessment
- Central Bangkok location: V Square Clinic, Thonglor Laser Center
- 0% installment plans are available with major credit cards
- Free consultation with our doctor, either in person or online — direct answers from our medical team at Thonglor Laser Center
Frequently Asked Questions (FAQ)
Q: Will I see results after just one session of Pico Laser?
A: Yes, depending on your skin condition and concerns, results can often be seen after the first session. However, for more noticeable and long-lasting improvements, 3 to 5 sessions are typically recommended.
Q: Does Pico Laser thin out the skin?
A: No, Pico Laser does not thin the skin. It doesn’t peel or remove the surface layer—instead, it breaks down pigment and rejuvenates the skin from within.
Q: Will my skin peel after Pico Laser?
A: Some patients may experience mild peeling, like dead skin flaking. This is not a side effect, but a natural part of the skin renewal process.
Q: Do I need downtime after Pico Laser?
A: No downtime is needed. You can return to your normal routine immediately, but you should avoid direct sunlight and apply sunscreen regularly.
Is Pico Laser Worth It?
Pico Laser is one of the most advanced technologies for treating pigmentation, acne marks, and scars. Many patients report noticeable improvement after treatment. Today, several brands of Pico Laser are available, each with unique strengths for addressing skin concerns.
If you’re unsure which Pico Laser machine or treatment type is best for you, feel free to visit V Square Clinic. We offer personalized assessments and treatment plans — all performed by experienced laser doctors.
Reference
- https://pubmed.ncbi.nlm.nih.gov/32282094/
- https://www.cynosure.com/product/picosure-pro/
- https://www.cynosurelutronicemea.com/product/pico-plus/
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