Neuramis Filler – A Korean Brand Gaining Attention
Neuramis is a filler brand that has garnered attention from many patients. Common questions include: What is Neuramis? Is it FDA-approved in Thailand? Why is it more affordable than other brands? Is it safe? How many versions are available? What’s the difference between the black and gold box versions? This article will explain everything you need to know about Neuramis filler.
Table of Content : Neuramis Filler
What Is Neuramis Filler?
Neuramis is a type of hyaluronic acid (HA) filler that is biodegradable and naturally dissolves over time. It is manufactured in South Korea and imported into Thailand by the company Medyceles. The product is often referred to by its packaging colors: black box and gold box. Because of its relatively low price compared to premium filler brands, Neuramis has become a frequently asked-about option.

Neuramis filler is manufactured using proprietary SHAPE Technology—a 2-step cross-linking process that enhances the gel’s elasticity and stability. This technology allows the filler to maintain its shape for longer periods and makes it suitable for injection in various facial areas. It also goes through an Enhanced Purification process, which reduces impurities and minimizes the risk of side effects.
How Many Versions of Neuramis Are There? How Long Do They Last?
As of May 2025, Neuramis is available in five versions certified by the KFDA (Korea), U.S. FDA, and EDQM (Europe). However, only three of these versions are approved by the Thai FDA:
- Neuramis Deep (Black box): The first version approved in Thailand. It does not contain lidocaine. The gel has medium viscosity, provides good volume, and is easy to mold. It can be used for various facial areas and lasts 6–8 months.
- Neuramis Deep Lidocaine: Similar in consistency to the Deep version, but includes 0.3% lidocaine to reduce discomfort during injection. Also lasts 6–8 months.
- Neuramis Volume Lidocaine (Gold box): The thickest and most elastic version in the lineup. It is ideal for correcting moderate to deep wrinkles and volume loss. Contains lidocaine and lasts about 6–9 months.
Other versions of Neuramis not listed above are not approved by the Thai FDA. These are often imported through unofficial channels and may not meet quality control standards. Improper storage conditions can increase the risk of complications, including adverse reactions after injection.
As for longevity, Neuramis typically lasts 6–9 months, depending on the version used and individual aftercare habits. Avoiding behaviors that accelerate filler breakdown can help extend its effectiveness.
Is Neuramis Filler Safe?
The answer depends on whether the filler used is authentic and FDA-approved. Unauthorized or “gray market” fillers often lack proper quality control and storage, leading to product degradation. This could result in reduced efficacy or a much shorter lifespan.
In more severe cases, counterfeit fillers made from substances like liquid silicone can pose serious risks. These can migrate or form hard lumps and cannot be naturally dissolved. Surgical removal is often the only solution.
To ensure a safe Neuramis injection, it is essential to choose a certified clinic that uses FDA-approved products and has experienced doctors who follow proper injection techniques in a hygienic medical environment.
Some clinics may not open the filler packaging in front of patients or may withhold the box afterward, citing stock-keeping policies. However, this raises concerns about authenticity.
For greater safety and peace of mind, patients should choose a clinic that opens the filler box in front of them and allows verification that it is a genuine Neuramis product officially imported into Thailand.
How to identify Neuramis Filler
Which Facial Areas Are Suitable for Neuramis Filler?
Each facial concern requires a specific type of filler, and the appropriate version and brand should be selected based on individual needs.
Neuramis is often used to treat moderate to deep wrinkles, sagging skin, and volume loss in various facial areas. Common injection sites include: Nasolabial folds, Temples, Chin, Apple cheeks, and Hollow cheeks.
Neuramis Filler Results at V Square Clinic
Neuramis Volume 2 CC was injected into the chin to enhance projection and improve lower-face harmony.
Neuramis Volume 2 CC was used to restore temple volume, and Neuramis Deep 2 CC was injected into the hollow cheeks to improve mid-face contour.
*These results are based on individual treatment responses and may vary from person to person.
How Do Neuramis, Juvederm, Restylane, and Belotero Differ?
- Neuramis (Korea): This Korean filler brand is widely used in both Thailand and internationally. Its main advantage lies in its affordability compared to other Thai FDA-approved fillers. However, a price that is unusually low may indicate that the product is a counterfeit or an uncertified gray-market product.
- Juvederm (USA): A highly popular filler brand from the United States, Juvederm is trusted by aesthetic doctors worldwide. It stands out with two proprietary technologies—Hylacross, known for its high flexibility and durability with facial movement, and Vycross, which enhances lifting and tightening results. Juvederm offers multiple formulas to suit different treatment areas and patients’ concerns.
- Restylane (Sweden): A well-established brand with a long history in the aesthetic industry. Restylane is certified by the U.S. FDA and is continually advancing its formulas. It features two key technologies—NASHA and OBT—which allow for a range of filler consistencies, supporting both structural lifting and deep wrinkle correction.
- Belotero (Switzerland): A reputable filler brand imported by Merz Healthcare (Thailand) Co., Ltd. It is known for its safety, high-quality formulation, and approval by the FDA in the U.S., Europe, and Thailand. Belotero is especially praised for its versatility and soft texture, making it ideal for nearly every facial area, while still achieving very natural-looking results.
How Is Neuramis Different from American Fillers?
Many patients wonder how Neuramis, a Korean-made filler, compares to American fillers—particularly Juvederm, which is one of the leading HA filler brands in the U.S.
Juvederm (USA)
Juvederm is a high-quality hyaluronic acid filler trusted by doctors worldwide. It meets regulatory standards set by both the U.S. FDA and Thailand’s FDA and is imported by Allergan Thailand—the same company that manufactures Botox Allergan.
Juvederm offers multiple formulations, each with different molecular weights, allowing doctors to choose the most suitable option for specific treatment areas. The results are typically very natural and long-lasting. Examples include:
- Juvederm Ultra Plus: lasts up to 8 months
- Juvederm Volift: lasts up to 12 months
- Juvederm Volite: lasts 8–12 months
- Juvederm Volbella: lasts up to 12 months
- Juvederm Voluma: lasts up to 18 months
- Juvederm Volux: lasts 18–24 months
Neuramis (Korea)
Neuramis is currently available in three Thai FDA-approved versions, all of which have fairly similar consistency. Because of its relatively large molecular structure, Neuramis is not suitable for more delicate areas like the tear troughs, where softer, finer fillers would be more appropriate. Using Neuramis in such areas may lead to unnatural results, such as firmness or lumpiness.
In terms of cost, Neuramis is generally about half the price of Juvederm. However, it also tends to have a shorter duration of effect.
What Fillers Does V Square Clinic Use?
At V Square Clinic, we exclusively use authentic dermal fillers that are FDA-approved and properly imported. Every product is stored and handled under strict temperature controls—from shipping to the point of injection—to preserve its quality at 100%.
We offer a curated selection of world-renowned brands trusted by doctors worldwide, including:
- Restylane (Sweden)
- Juvederm (USA)
- Belotero (Switzerland)
- Definisse (Italy)
- Teoxane (Switzerland)
Each brand is selected for its unique benefits in specific facial areas. Since no single filler suits every concern, having multiple options allows for personalized treatment planning.
For the best results, our experienced doctors evaluate each patient’s skin, goals, and facial structure to recommend the most suitable filler for their individual case.
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Aftercare Tips for Neuramis Filler
Aftercare for Neuramis filler is similar to that of other hyaluronic acid fillers. The following summary provides essential tips for both pre- and post-treatment care to support safe and effective results.
Final Thoughts – Is Neuramis Filler Worth It?
Neuramis is a great option for patients looking for an affordable filler to improve facial aesthetics. However, when it comes to long-term value, it may have a shorter lifespan compared to premium European and American fillers like Juvederm, Restylane, and Belotero. Additionally, Neuramis offers fewer product variations.
In contrast, European fillers approved by the Thai FDA come in a wider range of formulations, allowing doctors to better match the product with each patient’s skin condition and treatment area. For the best results and safety, it’s important to have your case evaluated by a qualified doctor who can recommend the most suitable option tailored to your needs.
Reference
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