
Nowadays, there are many brands of Botox available, each with its own advantages. The choice often depends on individual preferences or a doctor’s recommendation. Xeomin, commonly referred to as German Botox, is one of the most popular choices.
This article explores what German Botox Xeomin is, its pros and cons, how much it costs, and how to identify genuine Xeomin products.
Table of content : Xeomin
What is German Botox Xeomin?
“Botox” is a commonly used term worldwide, often understood as Botulinum toxin, which is used to reduce jaw size and smooth out wrinkles. However, in reality, Botox is a brand name of Botulinum toxin developed by Allergan, a company based in the United States.
In fact, many pharmaceutical companies can also produce Botulinum toxin. Each brand develops its own molecular structure and registers a proprietary trade name. Xeomin® is one such brand of Botulinum toxin, manufactured by MERZ PHARMA GMBH & CO. KGaA, a German pharmaceutical company.
German Botox Xeomin features a smaller molecular structure compared to other brands. The company uses a proprietary XTRACT Technology™ in the production process to eliminate unnecessary accessory proteins from the toxin molecule. As a result, Xeomin contains only the active neurotoxin, making the molecules smaller while still maintaining high effectiveness in blocking nerve signals.

Because German Botox Xeomin has undergone a process to remove unnecessary proteins, it results in a highly purified Botox with a low chance of resistance. Research has confirmed that injecting Xeomin in patients with a history of Botox resistance shows better results compared to other brands, provided the previous injection was at least 2–3 years ago.

A research study on Xeomin Botox injections found that 99.4% of participants showed no stimulation of antibody (NAbs) production against botulinum toxin, while 0.6% showed antibody presence, but the Botox still remained effective. Therefore, the study concluded that no cases in the trial exhibited resistance to Xeomin Botox.
Where can German Botox Xeomin be injected?
Xeomin Botox was developed by combining the advantages of Allergan and Dysport. Its properties sit between the American and British brands—highly purified with good diffusion. It provides natural-looking results without making the face feel too stiff, making it ideal for wrinkle reduction and facial contouring (Dermolift).
Xeomin can be injected in the same areas as other brands and is suitable for those who do not want excessive muscle shrinkage. It provides a lighter, more natural feel.
Injection areas for Xeomin Botox include:
- Jawline slimming.
- Upper arm muscle reduction.
- Calf muscle reduction.

Advantages of German Botox Xeomin
German Botox Xeomin is a highly purified botulinum toxin. Its manufacturing process involves removing unnecessary proteins from the toxin molecule. A key advantage of this brand is its low risk of triggering antibody development, even after multiple treatments. Therefore, it’s often recommended for both therapeutic and aesthetic purposes.
Research also supports that Xeomin provides better results in patients with a history of Botox resistance, especially if they have stopped Botox injections for 2–3 years.
How is German Botox Xeomin different from other brands?
Key features of Xeomin Botox include:
- XTRACT Technology™, which eliminates unnecessary proteins to create a highlypurified molecule.
- Low molecular weight, allowing for better diffusion and more natural results without excessive stiffness.
- Effectiveness in resistant cases, with potential benefits for patients who have developed resistance to other brands. However, since Botox resistance is not currently reversible, results cannot be guaranteed in every case.
Steps for Injecting German Botox Xeomin

Consulting a Doctor Before Getting Botox
- Consultation and Assessment
The doctor begins with a facial analysis and an evaluation of the patient’s skin condition to determine suitability for Botox treatment. - Product Selection and Verification
Once the Botox brand has been selected, the doctor must open the box in front of the patient. The expiration date and production lot should be checked, and the patient should be guided on how to verify product authenticity using brand-specific indicators. - Injection Process
The doctor uses a fine needle to inject the Botox directly into the target areas. To minimize discomfort, a numbing cream or ice pack is applied beforehand.
How Much Does German Botox Xeomin Cost?
Xeomin Botox for facial slimming (100 units) starts at approximately 15,999 THB.
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Possible Side Effects After Injecting German Botox Xeomin
Xeomin Botox is approved by both the U.S. FDA and Thailand’s Food and Drug Administration (Thai FDA), ensuring a high level of safety. However, it is crucial to verify the authenticity of the product and to receive injections only from experienced doctors.
Mild side effects such as soreness, tightness, or small needle marks after injection are common and not considered harmful. Allergic reactions are rare and typically present as small rashes, which usually resolve on their own.
More serious side effects may include:
- Infections and inflammation, usually caused by unlicensed practitioners or clinics with poor hygiene and improper sterilization.
- Drooping eyelids, crooked mouth corners, incomplete smile, or a stiff-looking face—these can result from injecting Botox near sensitive areas, such as close to the upper eyelid, to treat crow’s feet. Improper technique or incorrect dosage and placement can cause the surrounding muscles to weaken, leading to drooping eyelids or other complications.
That said, choosing a certified clinic with experienced doctors and genuine Xeomin significantly reduces the risk of serious complications.
Does German Botox Xeomin Cause Resistance?
Xeomin is a highly purified form of botulinum toxin, so the risk of developing resistance is minimal. Moreover, in cases where resistance to other brands has developed, studies suggest there is still about a 50% chance that Xeomin may remain effective.
How to Identify Authentic German Botox Xeomin
How to identify genuine German Botox Xeomin:
- Scratchable QR code located on the top of the box that can be scanned for verification.
- Thai-language documentation included in the packaging.
- Matching lot numbers on both the outer box and vial label.
- Lot number and clinic verification available through Merz Aesthetic Thailand at 02-026-1111.
- Powder form in the vial, not liquid; it must be mixed with saline by the doctor before injection.

Reviews of German Botox Xeomin Injections
Before deciding on Xeomin Botox injections, it is important to research the clinic, review the doctor’s qualifications, and read real customer reviews. This helps ensure satisfying results and reduces the risk of side effects such as uneven smile, asymmetry, or droopy eyelids.

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