HArmonyCa Hybrid Filler

In today’s world where aesthetics and skin health are a growing priority, a cutting-edge innovation like HArmonyCa is quickly becoming a popular choice. It does more than just fill facial wrinkles—it also effectively stimulates collagen production from within.
HArmonyCa is known as a 2-in-1 filler solution, offering both skin rejuvenation and facial contouring in a single treatment. This article will introduce you to HArmonyCa in detail—its advantages, limitations, preparation tips before the injection, and complete post-treatment care guidelines.
Table of Content : HArmonyCa
What Is HArmonyCa?
HArmonyCa is the latest generation of dermal filler developed by Allergan, a global leader in aesthetic innovation based in the United States. What sets HArmonyCa apart from traditional fillers is its unique combination of two powerful components—Hyaluronic Acid (HA) and Calcium Hydroxyapatite (CaHA)—blended in a single syringe.

Key Components of HArmonyCa
- Hyaluronic Acid (HA) A well-known dermal filler substance with exceptional water-binding capabilities—it can hold up to 1,000 times its weight in water. HA helps plump the skin, add hydration, and smooth out fine lines immediately after injection. It’s often used to treat areas like nasolabial folds, under-eye hollows, and add volume for a more youthful look.
- Calcium Hydroxyapatite (CaHA) A standout ingredient known for its ability to stimulate fibroblasts, the deep skin cells responsible for collagen production. Collagen is a vital protein that strengthens, firms, and tightens the skin. Thanks to CaHA, the skin continues to look youthful and firm long after the HA has gradually dissolved.
How Does HArmonyCa Work? Mechanism of Action After Injection
When HArmonyCa is injected into the dermis and subdermal layers, the Hyaluronic Acid (HA) takes effect immediately—filling fine lines and restoring volume in areas such as the nasolabial folds, marionette lines, and jawline. The result is noticeably smoother, plumper skin right from the first treatment.
Following this, Calcium Hydroxyapatite (CaHA) activates fibroblasts in the skin to stimulate new collagen production. This collagen regeneration process occurs gradually over the next 1–2 months, strengthening the skin, improving elasticity, and creating a firmer, more youthful appearance. These long-term effects can last up to 1–3 years, significantly longer than typical HA-based fillers.
What Sets HArmonyCa Apart from Traditional Fillers?
Most dermal fillers available today are made exclusively with Hyaluronic Acid (HA), which focuses on filling wrinkles and hydrating the skin. However, HArmonyCa goes a step further by including Calcium Hydroxyapatite (CaHA)—a component that actively stimulates long-term collagen production. This dual-action formula not only offers immediate volume but also rebuilds the skin’s internal support structure over time.
Combined Short-Term and Long-Term Benefits of HArmonyCa
HArmonyCa is specially designed to deliver benefits on both a short-term and long-term scale:
Short-term Benefits
- Immediate enhancement of facial volume after injection
- Improved skin hydration and a healthier-looking complexion
- Enhanced facial contours for a more defined appearance
Long-term Benefits
- Ongoing stimulation of new collagen production
- Progressive skin tightening and lifting
- Reduced skin laxity and visible signs of aging over time

Which Facial Areas Can HArmonyCa Be Injected Into?
HArmonyCa is typically injected into the lateral areas of the face, commonly referred to as the C-shape zone. This includes the chin, jawline, mandibular angle, up to the cheeks and midface region. These areas are often affected by skin sagging, loss of firmness, and deep wrinkles.
Treating these zones helps restore lost volume and provides facial lifting benefits, resulting in a more youthful, naturally contoured appearance.
Who Is HArmonyCa Suitable For?

HArmonyCa is ideal for individuals looking to rejuvenate their skin naturally while enhancing facial contours. It’s especially suited for those experiencing early signs of skin laxity, collagen depletion, visible wrinkles, or an aging appearance. Generally, people aged 25 and above who want noticeable and long-lasting results would benefit from HArmonyCa.
How Much Does HArmonyCa Cost?
The typical price for HArmonyCa is around 2x,xxx THB per syringe, although actual costs may vary depending on each clinic’s ongoing promotions.
Interested in getting HArmonyCa at V Square Clinic?
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HArmonyCa Injection Procedure
- The doctor assesses the patient’s skin condition and identifies specific problem areas to create a personalized treatment plan.
- The skin is cleansed thoroughly to prevent infection.
- The HArmonyCa product is unboxed in front of the patient to confirm authenticity and ensure it is FDA-approved.
- HArmonyCa is then injected into the targeted treatment zones.
- During the injection, ice packs or cooling gels are applied to minimize discomfort and reduce the chance of bruising.
- After the procedure, the doctor gently massages the treated area to help distribute the filler evenly and enhance its effect.
How to Prepare Before Getting HArmonyCa Injections
To achieve the best results and minimize the risk of side effects, follow these preparation guidelines:
- Avoid certain medications and supplements such as aspirin, NSAIDs, vitamin E, fish oil, garlic, ginseng, St. John’s Wort, Ginkgo Biloba, and evening primrose oil for at least one week prior to treatment to reduce bruising.
- Refrain from using exfoliating products or shaving/waxing the treatment area for at least one week before the procedure to prevent skin irritation.
- Avoid laser treatments or facial massages at least 3 days before the injection to reduce inflammation.
- Do not consume alcohol at least 24 hours before the procedure to prevent swelling and bruising.
- Avoid activities that increase blood circulation, such as saunas or cardio exercise, for at least 24 hours.
- Inform the doctor of any chronic illnesses or regular medications to ensure safety and proper treatment planning.
Procedure Duration and Pain Level
The HArmonyCa injection process takes around 20–30 minutes. Patients may experience slight discomfort, similar to a pinprick, or mild tightness as the filler is injected. Most patients tolerate the procedure well and can resume normal activities immediately afterward.
What to Look for in a Clinic and Injector
- Licensed clinic with a strong reputation
- Qualified and experienced injector who is a medical professional
- Authentic, verifiable products used for every treatment
- Reliable patient reviews and testimonials that reflect real experiences
- Reasonable pricing that isn’t suspiciously low or too good to be true
Aftercare Tips Following HArmonyCa Injections
- Avoid touching or massaging the treated area for 1–2 weeks.
- Refrain from intense physical activity, sauna use, or alcohol consumption for 24–48 hours.
- Apply cold compresses to minimize swelling.
- Stay well-hydrated by drinking plenty of water.
- Monitor for unusual symptoms such as significant redness, swelling, or lumps. If these occur, contact the doctor promptly to ensure proper care.
Real Patient Reviews – HArmonyCa Injection Experiences

Before injection – Immediately after – 5 months later

Before injection – 1 month later – 1 year later
*Results are based on individual cases.
Summary of HArmonyCa Results Over Time
- Immediately after injection: Visible improvements in skin firmness, smoothness, and reduction in wrinkles and fine lines.
- 3–6 months after: Noticeable increase in collagen production from CaHA, resulting in firmer and more lifted skin.
- 1 year after: Skin remains elastic and healthy thanks to newly stimulated collagen structure, with results lasting approximately 1–3 years.
HArmonyCa vs Other Filler Brands (Juvederm, Restylane)
Popular fillers like Juvederm and Restylane are primarily composed of Hyaluronic Acid (HA) and work mainly by plumping the skin and reducing wrinkles.
HArmonyCa stands out by combining both Hyaluronic Acid (HA) and Calcium Hydroxyapatite (CaHA) in a single syringe. This dual-action formula offers immediate volume restoration along with long-term collagen stimulation, delivering more comprehensive and lasting results.
In addition to typical HA-based fillers, other collagen biostimulators like Sculptra, Radiesse, and Profhilo offer different mechanisms and outcomes. Here’s a quick comparison:
| Comparison | Key Differences |
|---|---|
| HArmonyCa vs Radiesse | Both contain CaHA for collagen stimulation, but HArmonyCa also includes HA, offering instant volume and visible results right after injection. |
| HArmonyCa vs Sculptra | Sculptra uses PLLA to stimulate collagen over time. Results are not immediate and typically begin to show after 2–3 weeks. Multiple sessions are often required for optimal results. |
| HArmonyCa vs Profhilo | Profhilo is a non-crosslinked HA that hydrates and smoothens the skin. It does not provide instant volume or lifting like HArmonyCa, making it more suitable for overall skin rejuvenation. |
Are There Any Side Effects or Risks with HArmonyCa?
HArmonyCa is considered highly safe and has been approved by both the U.S. FDA and the Thai FDA. Minor side effects such as redness, swelling, or bruising at the injection site may occur but typically resolve within 1–2 weeks.
Frequently Asked Questions About HArmonyCa (FAQs)
How long does HArmonyCa last?
On average, results from HArmonyCa last around 1–3 years, depending on individual skin care and lifestyle factors.
How often can you get HArmonyCa injections?
It is generally recommended to wait 6–12 months between sessions, depending on your skin condition and your doctor’s advice.
Are there any contraindications or who should avoid HArmonyCa?
HArmonyCa is not recommended for pregnant or breastfeeding individuals, those with known allergies to filler components, or individuals with certain underlying medical conditions.
Conclusion – HArmonyCa: A Unique Innovation in Fillers
HArmonyCa combines Hyaluronic Acid (HA) and Calcium Hydroxyapatite (CaHA) in one syringe, delivering immediate plumping results while simultaneously stimulating new collagen production over time. It’s a worthwhile and comprehensive solution for those seeking natural skin rejuvenation with long-lasting benefits.
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