Meso Fat Injection (Meso Fat)

Meso Fat injection is a non-surgical fat reduction technique suitable for those looking to slim specific body areas, especially when diet and exercise alone do not provide the desired results. It is commonly used to contour the face, reduce chubby cheeks, a double chin, upper arms, thighs, calves, and hips.
On the other hand, athletes or those who weight train may develop localized muscle bulk in certain areas they’re not satisfied with. In such cases, Botox can help reduce muscle volume.
The appropriate treatment depends on the target area, which will be explained in detail below.
Table of Content : Meso Fat
What is Meso Fat?
Meso Fat refers to the injection of a fat-dissolving solution directly into the subcutaneous fat layer. This method helps eliminate localized fat and cellulite without surgery, effectively contouring and tightening the body as desired.
The mechanism of Meso Fat involves breaking down fat cells using active ingredients. The broken-down fat is naturally eliminated through the body’s excretory system—via urine, stool, or sweat. Key ingredients include:
- Artichoke Extract (Cynara Scolymus): Stimulates coenzyme synthesis during anabolism, reduces fat tissue formation, and fatty acid synthesis. Ideal for those with excess weight and localized fat (e.g., cheeks, cellulite).
- Mesostabyl (Polyunsaturated Phosphatidylcholine): Activates the enzyme lipase, reduces triglyceride production, and inhibits cholesterol synthesis in tissue.
- L-Carnitine: Promotes the conversion of fat into energy by boosting fat metabolism and increasing fat utilization.

Note: Formulations may vary slightly between brands, but most include natural extracts as their active ingredients.
L-Carnitine in Meso Fat: Turning Fat Into Energy
L-Carnitine is a naturally occurring substance produced by the liver and kidneys from the amino acids lysine and methionine. It plays a crucial role in transporting fatty acids into the mitochondria, where fats are converted into energy. Its fat-burning function is further enhanced by the following:
- Triglyceride breakdown: Enhances fat decomposition
- Tyrosine: Boosts fat metabolism
- Aesculus hippocastanum (Horse Chestnut): Reduces fluid retention
- Juglans regia (Walnut): Enhances blood circulation and metabolism
- Nicotiana tabacum: Stimulates catecholamine release, promoting lipolysis
In short, L-Carnitine boosts Meso Fat’s effectiveness by accelerating triglyceride breakdown, especially when combined with other lipolysis-enhancing and circulation-boosting ingredients.
What Can Meso Fat Help With?
Meso Fat works by breaking down fat, making it ideal for people who want to slim specific body parts more quickly than with traditional methods. It’s commonly used for slimming the cheeks, jawline, upper arms, thighs, hips, and any area with stubborn fat buildup.

The illustration above shows how Meso Fat breaks down fat post-injection and helps eliminate it from the body, speeding up fat reduction results.
Where Does the Fat Go After Meso Fat Injection?
Once injected, the Meso Fat solution binds to fat cells and initiates a fat breakdown process. These dissolved fats are then naturally eliminated through urination, bowel movements, or sweat.
Meso Fat vs. Botox—What’s the Difference?
Meso Fat breaks down fat, while Botox works by temporarily relaxing the muscles. When muscles are inactive for a while, they shrink in size (atrophy), which reduces volume in that area for about 6–8 months.

Both treatments can effectively reduce the size of specific areas. A skilled doctor can assess whether fat or muscle is the main concern and select the most effective approach. In some cases, combining both together can enhance results more quickly.
Is Meso Fat Dangerous? What Are the Warnings From the Thai FDA?
There are two main types of “dangerous” Meso Fat formulas that the Thai FDA has warned about:
- Steroids : Steroids are normally used in dermatology for acne or keloid treatment in low doses. However, they are sometimes illegally mixed in high amounts into unauthorized Meso Fat formulas to cut costs and provide rapid results. Repeated injections can cause swelling, inflammation, and infection because steroids suppress the immune system.

Steroids used in illegal Meso Fat often appear as cloudy white or clear white liquids. Always ask to see the brand and verify the packaging before any injection.
- Filler Dissolver (Hyaluronidase) : While Hyaluronidase is safe when used to dissolve fillers, some unlicensed clinics misuse it in large doses for fat reduction. This rapidly breaks down collagen, causing sagging and premature wrinkles. Many online “Meso Fat” products are repurposed Hyaluronidase used dangerously.

Because Meso Fat is so popular—especially for cheeks and double chin—some patients opt for unlicensed “backpack doctors” due to low cost. However, these providers often use fake or unsafe drugs smuggled illegally, posing serious risks of infection, contamination, and poor injection techniques.
If considering Meso Fat injections, always choose a licensed clinic that uses FDA-approved products. Ask to see the brand name before treatment to ensure safety and transparency.
Where Can Meso Fat Be Injected?
Meso Fat injections can target multiple areas. The most popular applications include facial fat reduction—particularly the cheeks, jawline, and under the chin—to create a slimmer, more contoured look. Other injectable areas include the abdomen, upper arms, thighs, calves, and hips.
Meso Fat can also be combined with Botox to target both fat and muscle, helping refine both facial and body contours more effectively.

Meso Fat for Cheek Slimming vs. Jaw Reduction Botox vs. Buccal Fat Removal
For those seeking facial contouring to achieve a slimmer and more defined shape, several medical procedures are available. These include Meso Fat for cheek slimming, Botox for jaw muscle reduction, and buccal fat removal surgery. Each approach suits different needs:
Meso Fat for Cheek Reduction
Meso Fat injections can be used to reduce fat in area #1 (as labeled in the image) and area #3. However, results may vary depending on individual lifestyle habits such as diet (e.g., sugar or greasy foods), lack of exercise, or frequent late-night eating. Generally, effectiveness ranges from approximately 60–70%.

Meso Fat is ideal for individuals with moderate subcutaneous fat in the cheeks who prefer a non-surgical option to reduce puffiness. It can also be combined with other treatments to enhance results and further define the face.
Review of combined procedures using Meso Fat

Before – Immediately After – 2 Weeks – 1 Month
Treatment: 2cc chin filler + 100U jaw Botox + 20cc Meso Fat + 4 Mint Threads + 600-line
Ultraformer III

Before – Immediately After – 2 Weeks – 1 Month
Treatment: 2cc under-eye filler + 2cc chin filler + 40cc Meso Fat + 100U jaw and facial contouring Botox + 6 PDO threads + 600-line Ultraformer III
*Results may vary based on individual clinical conditions
Jaw Reduction Botox
For individuals who want to slim their cheeks (area #1) but have prominent jaw muscles, Botox may be a more suitable choice. This can be assessed by clenching the teeth—if the jaw muscle bulges, jaw Botox is likely needed.
Botox works effectively on the masseter muscle (area #2), which in turn makes the cheek (area #1) appear smaller due to the two areas pressing against each other. Botox can also be combined with Meso Fat for more comprehensive slimming.

Before – Immediately After – 2 Weeks – 1 Month
Treatment: 2cc chin filler + 1cc midface filler + 100U jaw Botox + 60cc Meso Fat + 600-line Ultraformer III
*Results may vary based on individual clinical conditions
This case involved excess mass in both the jaw and cheeks, plus a short chin. The combination of Meso Fat, jaw Botox, and chin filler helped create a naturally slimmer and more balanced facial profile.
Buccal Fat Removal
Buccal fat removal is a surgical procedure that targets the Buccal Fat Pad (area #3). It offers nearly 100% fat reduction but requires high surgical precision. If too much fat is removed, it may cause hollow temples or sagging cheeks.

However, this surgery cannot remove superficial fat in area #1 (the fat just beneath the skin), which is often what patients want reduced. Liposuction is sometimes considered, but it carries a high risk of nerve damage and facial asymmetry.
Therefore, for area #1, non-surgical options such as Botox and Meso Fat are generally recommended, as they are safer and more targeted.
Ultimately, choosing the right procedure—or a combination—depends on individual concerns, desired outcome, budget, and downtime.
Meso Fat vs. Jawline Lift Botox vs. HIFU vs. Chin Liposuction
For those struggling with a double chin, sagging under the chin, or significant fat accumulation under the jawline, several effective medical options can be combined for a slimmer, more sculpted look.
Meso Fat for Double Chin Reduction
A double chin often results from accumulated fat and skin laxity as we age. If left unmanaged—combined with poor diet or lack of exercise—it becomes more noticeable.
Meso Fat can reduce about 10–15% of fat cells with each session, helping slim down the double chin. For enhanced tightening, it’s best to pair with jawline lift Botox.

HIFU Ultraformer for Chin Tightening
Energy-based lifting devices are another effective way to reduce under-chin fat and enhance overall facial tightness.
HIFU (High-Intensity Focused Ultrasound), specifically Ultraformer III, and Ultraformer MPT delivers ultrasound energy to stimulate collagen production deep beneath the skin. It reduces chin fat, tightens the jowls, and sharpens the jawline. While more expensive than Meso Fat, results from HIFU typically last longer.


Chin Liposuction
Chin liposuction can also be used to remove fat under the chin, but it often causes more swelling and bruising due to the area’s high blood vessel density. Severe bleeding may even pose a risk of airway compression.
Therefore, this procedure should only be performed in a hospital setting with proper safety measures.
Is Meso Fat Injection Effective for Abdomen, Arms, Thighs, and Calves?
Meso Fat for Abdominal Fat Reduction
Meso Fat injections can help reduce abdominal fat and contour the waistline. However, to maintain long-term results and prevent fat from coming back, it’s essential to pair the treatment with healthy habits, particularly proper diet and regular exercise.
Patient Reviews: Meso Fat (Lipo VSQ) for Stomach

Lipo VSQ, 2 vials for abdominal fat reduction

Lipo VSQ, 2 vials for lower abdomen + 2 vials for love handles
*Results may vary depending on individual clinical conditions.
For more definitive and long-lasting results, CoolSculpting is another option. It uses controlled cooling to freeze and permanently eliminate fat cells. However, it tends to be more expensive than Meso Fat.
Meso Fat for Upper Arms and Thighs
When targeting the arms or thighs, it’s important to determine whether the excess volume is due to fat or muscle.
- If it’s fat, Meso Fat is recommended.
- If it’s muscle, Botox works better for slimming.


*Results may vary depending on individual clinical conditions.
Botox for the upper arms can also create a slimmer appearance by reducing shoulder width. For thighs, if there’s a significant amount of fat, Meso Fat may not be cost-effective. In such cases, liposuction or CoolSculpting (for non-surgical fat reduction) would be more suitable to reduce volume effectively.
Meso Fat for Calves
For calves, Meso Fat is generally not recommended. Most patients with bulky calves have well-developed muscle, often due to activities like cycling, running, wearing heels, or frequent walking. In these cases, Botox provides more noticeable and consistent results.
Example: Botox for Calf Slimming

*Results may vary depending on individual clinical conditions.
A full reduction typically requires 300–400 units per leg, but for safety, the body can only tolerate around 300 units per 3-month period. Injecting too much at once can impair mobility, so we recommend spacing treatments, starting wit00 units per session.
At V Square Clinic, new vials are opened in front of each patient. Patients can see the full dose being drawn and may take the empty box and vial home as proof of authenticity.
Benefits of Meso Fat Injection
- No downtime required
- Minimal swelling or bruising (mild swelling may occur in the first 3–4 hours)
- Quick procedure time
- Fast-acting results
- Safe
- Affordable
Meso Fat is a quick, non-surgical way to eliminate localized fat—ideal for people who want visible results without undergoing surgery or taking time off for recovery.
Drawbacks of Meso Fat Injection
Unlike liposuction, Meso Fat does not offer instant results. It usually takes 1–2 weeks for the solution to take full effect.
Additionally, it may not be suitable for individuals with a large volume of fat. In such cases, 4–5 sessions may be required for noticeable results. A doctor should assess whether Meso Fat is appropriate based on the fat volume in the targeted area.
Meso Fat vs. Liposuction: Suitable Treatment Areas and Precautions
In areas with numerous blood vessels or vital nerves—like the face and neck—liposuction is not recommended due to higher risks of complications. Instead, Meso Fat or skin-tightening devices offer safer, more precise contouring.

What to Expect After Meso Fat Injection
Patients may experience temporary swelling at the injection site due to the fluid volume. This typically subsides within 3–4 hours as the solution is absorbed. There’s no pain or inflammation, though minor needle-site swelling is normal.
Aftercare Tips for Cheek and Chin (Double Chin) Injections
- Avoid massaging or pressing on the treated area—the solution will naturally be absorbed.
- Drink at least 2 liters of water daily to help flush fat through the body.
- Adjust your eating habits to prevent fat from returning.
- Avoid facials, sauna, or laser treatments for at least 1 week post-treatment.
- Avoid alcohol after treatment to support the fat breakdown process.
How Long Does Swelling Last After Meso Fat Under the Chin?
Swelling usually subsides within 3–4 hours after injection. Some patients may feel that their face is noticeably swollen, but this is completely normal and will reduce as the fat-dissolving solution starts to work.
How Many Sessions of Meso Fat Are Needed?
Results may start to appear within 5–7 days, with the full effect visible around 2–3 weeks post-injection.
Patients with a larger volume of fat may need 4–5 sessions to achieve significant improvement. Repeating the treatment as advised by your doctor can also help prolong and enhance the results.
How Long Do the Results of Meso Fat Last?
The duration of results depends largely on lifestyle habits and diet. On average, results can last 2–3 months. Maintaining a healthy lifestyle—avoiding fried and fatty foods—can help preserve the results for longer.
Which Meso Fat Brand Is Best?
There are several Meso Fat brands available, and the best one depends on each individual’s needs. It’s best to consult with a qualified doctor, who will assess your concerns and recommend the most suitable formula. Each brand has its strengths and properties tailored to different areas and patient goals.
Meso Fat Price & Promotions at V Square Clinic
Meso Fat pricing at V Square Clinic varies based on the brand used.
Interested in Meso Fat at V Square Clinic?
Click here to view the latest promotions.

Q&A: Common Questions About Meso Fat Injections
Q: Is Meso Fat injection painful?
A: Meso Fat injections may cause mild discomfort during the injection or while the solution is being administered. For particularly sensitive patients, cold compresses or numbing cream can be used to reduce discomfort. If you’re concerned about pain, rest assured that it’s typically minimal.
Q: How soon will I see results after Meso Fat injection?
A: You may begin to see results after the first session, about 10–15% fat reduction. Full results usually appear within 1 to 3 weeks.
Keep in mind, how soon you see results depends on individual factors like the amount of fat in the treated area and your lifestyle. For more noticeable results, follow-up sessions as recommended by your doctor are highly beneficial.
Q: How many cc are in one Meso Fat vial?
A: One vial of Meso Fat contains 10 cc. Your doctor will assess your facial or body structure and recommend the appropriate volume based on your specific needs.
Q: Is abdominal fat reduction via Meso Fat injection painful?
A: You may feel a slight sting during the injection process. However, it’s far less painful than abdominal liposuction. Ice packs can also be used to minimize discomfort during the procedure.
Q: Can I buy Meso Fat online and inject it myself?
A: Not recommended. Products sold online may be counterfeit or unsafe. Only certified doctors can legally obtain Meso Fat solutions approved by the FDA.
Additionally, Meso Fat injections require a thorough understanding of facial and body anatomy, especially injection depth and distribution technique. Each patient has a unique fat and muscle structure, and improper technique could lead to complications.
Q: Will Meso Fat leave lumps or uneven areas?
A: When high-quality Meso Fat is used and the doctor employs the correct dispersion technique, the solution is naturally absorbed and should not form lumps.
Q: Can pregnant women get Meso Fat injections?
A: Meso Fat injections are not recommended during pregnancy. It’s best to wait until after childbirth before considering treatment.
Summary—Is Meso Fat Worth It?
Meso Fat is an effective solution for targeted fat reduction, delivering visible results without surgery. However, for the best outcome and safety, it’s important to use authentic, FDA-approved products and be treated by an experienced physician who can accurately assess your needs and determine the right dosage.
If you’re considering Meso Fat injections, always choose a licensed, reputable clinic that adheres to medical standards and ensures transparency throughout the treatment process.
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