Gouri – A Collagen Biostimulator for Skin Rejuvenation
Healthy, hydrated, collagen-rich skin—like baby—soft skin—is a trending skincare goal. One popular treatment gaining attention is Gouri, the world’s first injectable collagen stimulator using PCL (Polycaprolactone), a material previously used in thread lifting procedures. It’s now reformulated into a fully liquid form and injected into the skin to restore its structure and boost collagen production. This leads to healthier, younger-looking skin over time.
If you’re curious about Gouri, this article provides everything you need to know—what it is, how it works, how it compares to other treatments, suitable injection sites, ideal candidates, cost, timeline for results, side effects, and more. Let’s explore it together.
Table of Content : Gouri
What is Gouri?
Gouri is a fully liquid PCL (Polycaprolactone) injectable that stimulates collagen production beneath the skin, helping maintain youthful skin. It’s 100% bioresorbable, leaving no residue in the body, and has been approved by Thailand’s FDA. Gouri revitalizes aging or damaged skin from within, offering long-lasting improvements in skin quality and youthfulness.
The core component of Gouri is PCL—the same material used in dissolvable medical threads. What sets Gouri apart is its patented CESABP technology that converts PCL into a fully liquid form, unlike traditional microparticle formats.
Because it is a fully liquid solution, Gouri requires no reconstitution, reducing contamination risks. It is injected at just 2–4 points for full facial effect, minimizing discomfort while delivering results that last up to one year.
How Gouri Works
Gouri activates fibroblasts—cells responsible for producing collagen and elastin—through a natural stimulation process. As collagen levels increase, the skin becomes more hydrated, smoother, firmer, and more refined. Fine lines fade, pores tighten, and the overall skin texture visibly improves.
Comparing Gouri to Other Skin Treatments
Gouri vs. Filler Skin Booster
Filler skin boosters use hyaluronic acid (HA) in gel form to instantly hydrate and plump the skin, improve elasticity, reduce fine lines, and treat acne scars. Popular brands include Belotero Revive, Restylane Vital Light, and Skinvive by Juvederm. The choice of brand should be determined by a qualified doctor.
Gouri differs by using PCL in a liquid form to stimulate the body’s natural collagen production. Unlike HA fillers that hydrate the skin instantly, Gouri gradually improves firmness and elasticity from within.
Gouri vs. Rejuran
Rejuran is a skin booster made from polynucleotides (PN) derived from salmon DNA. It enhances hydration and glow—often referred to as the “glass skin” effect. Suitable for those with dry, dull skin, Rejuran provides quick recovery but shorter-lasting results than Gouri.
Gouri is a collagen biostimulator that offers longer-term results, especially for aging or collagen-depleted skin, helping maintain youthful, hydrated, resilient skin.
Gouri vs. Sculptra
Sculptra uses Poly-L-Lactic Acid (PLLA) in powder form, reconstituted with sterile water before injection. It stimulates natural collagen growth in deeper layers and typically lasts up to 2 years.
Gouri, on the other hand, uses PCL in a fully liquid form, requiring no reconstitution. It’s easier to administer but has a shorter longevity than Sculptra.
Gouri vs. Exosome Therapy
Exosome treatments deliver over 1,000 bioactive molecules to rejuvenate and repair skin, promoting tissue regeneration and deep hydration. Visible results appear within 3–7 days and can last 6–12 months.
Gouri vs. Mesotherapy
Mesotherapy involves injecting vitamins and active ingredients into the middle skin layer to improve tone, brightness, and hydration. While it delivers quick results, its effects are shorter-lived and require frequent treatments.
In contrast, Gouri, injected at only 2–4 points, offers less discomfort and longer-lasting results.
Gouri vs. Botox
Botox (Botulinum Toxin Type A) works by relaxing facial muscles to reduce wrinkles. Gouri, in contrast, stimulates collagen production to naturally fill fine lines and is suitable even for patients resistant to Botox.
Gouri vs. Thread Lifting
Thread lifting uses dissolvable threads like PDO, PCL, or PLLA to lift and contour facial features. It delivers immediate, visible lifting. Gouri focuses on skin quality improvement through collagen stimulation, with gradual but natural results.
Gouri vs. Skin Tightening Devices
Devices like HIFU, Ulthera, and Thermage use ultrasound or radiofrequency to heat skin layers and stimulate collagen. The advantage is that there are no incisions, making them suitable for those who are afraid of needles. Results become noticeably visible after 3 months or more.
By comparison, Gouri also promotes collagen, but shows results within 1 week of injection. For advanced aging or sagging, combining both treatments may enhance results.
Where Can Gouri Be Injected?
Gouri can be injected into any skin area, but common sites include the face, neck, and hands, where collagen stimulation is most beneficial.
Who Is Gouri Suitable For?
- Individuals with fine lines around the eyes, under-eyes, or mouth
- People with dull, tired-looking skin
- Those experiencing skin laxity and collagen loss
- Individuals with dry, dehydrated skin and enlarged pores
- Adults aged 18 and above looking to maintain youthful skin and prevent aging
- People seeking long-lasting skin improvements without frequent treatments
- Those who want to avoid traditional fillers
Who Should Avoid Gouri?
- Pregnant or breastfeeding individuals
- Anyone allergic to PCL
- Individuals with autoimmune disorders (e.g., SLE) or those on immunosuppressants
- People taking anticoagulants or NSAIDs—please pause for at least one week and consult your doctor beforehand.
What Are the Benefits of Gouri?
- Stimulates collagen and elastin production for firmer, more elastic skin
- Reduces wrinkles and sagging
- Repairs skin damaged by sun exposure and pollutants
- Deeply hydrates and refines skin texture
- Smooths deep facial lines for a natural finish
- Brightens skin tone and reduces pigmentation, redness, and acne scars
- Promotes inside-out skin rejuvenation and slows the aging process
Gouri Injection Process
- Cleanse the face with warm water
- Take an antihistamine 30 minutes before the procedure
- Apply a topical anesthetic for 20–30 minutes
- Remove the anesthetic with alcohol-soaked cotton
How Much Does Gouri Cost?
Gouri starts at approximately 16,000 THB per cc.
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How to Care for Skin After Gouri
- Avoid touching, scratching, or massaging the injection site
- Refrain from applying creams on needle sites for 24 hours
- Avoid alcohol and smoking for at least 24 hours
- Stay away from direct sunlight, saunas, or outdoor sports
- For the first week, avoid swimming and intense exercise
- Avoid energy-based devices (RF, Thermage, HIFU, Ulthera) for 1 month
Is Gouri Safe?
Gouri is a premium collagen stimulator approved by Thailand’s FDA and CE-certified internationally. It is a fully liquid solution with no microparticles, reducing contamination and vascular occlusion risks. It is biodegradable and leaves no harmful residue.
How to Spot Authentic Gouri
- Look for the non-removable Edencolors hologram sticker on both sides of the box
- Check the Hidden Tag sticker for scan verification on the back
- Inside the box, find the yellow sticker with two sections:
- Top: For doctors
- Bottom: For patients
- Ensure matching lot numbers in 3 spots on the box, or verify with Edencolors Thailand
Precautions Before Gouri Injection
Gouri can be combined with Botox, fillers, HIFU, Ulthera, or Thermage. However, avoid combining it with similar skin-boosting procedures such as mesotherapy, PRP, Rejuran, or Sculptra to prevent interaction or reduced effectiveness. If desired, wait at least 1 month between treatments.
Potential Side Effects After Gouri
Mild redness, swelling, bruising, or itching at the injection sites may occur and typically resolve within 2–3 days. In some cases, swelling may appear between days 5–10 as the product starts to work. This is normal and not a cause for concern.
Is Gouri Worth It?
Gouri is a safe and effective collagen stimulator approved by medical authorities. It revitalizes skin, tightens and plumps, and delays aging with minimal injections. It requires no downtime and results last 6–12 months, longer than many skin treatments. With a low risk of vascular occlusion, it is ideal for busy individuals seeking long-term skin improvement.
Frequently Asked Questions About Gouri
How Many Gouri Sessions Are Needed?
Results may be seen after the first session. For optimal results, 3 initial sessions spaced 1 month apart are recommended, followed by 1–2 maintenance sessions every 3–6 months.
When Will I See Results From Gouri?
You may begin seeing improvements within 1–2 weeks as collagen production is activated. Your skin will feel firmer, more hydrated, and fine lines will begin to fade.
How Long Does Gouri Last?
Results from Gouri typically last 6–12 months before the product naturally dissolves. Longevity depends on your skin condition and post-care habits.
Gouri Skin Rejuvenation Summary
Gouri is a standout collagen biostimulator that improves skin texture, reduces fine lines, and delivers a firm, youthful glow. Results are visible within 1–2 weeks and last up to 12 months, making it ideal for those who want long-term benefits without frequent touch-ups.
If you are dealing with skin concerns, feel free to get an initial consultation. At V Square Clinic, we offer free online consultations with our experienced doctors.
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