Is Restylane Filler a good choice?

Restylane is one of the most well-recognized hyaluronic acid–based dermal filler brands from Sweden. It has been widely trusted by physicians around the world and is officially approved by the FDA.
For those wondering whether Restylane is a good filler, who it is suitable for, which areas it can treat, and whether it is worth the cost—this article provides a complete overview of the brand.
Table of Content : Restylane
Is Restylane Filler Good? What Are Its Features?
Restylane Filler is a Hyaluronic Acid (HA) filler—a type of naturally occurring substance found in our own body. Due to its biocompatibility, it is considered very safe and rarely causes allergic reactions or irritation.
This versatile filler can be used in multiple facial areas, especially under the eyes. It helps fill in both deep and superficial wrinkles, restoring a firmer, more youthful appearance to the skin.


Restylane is one of the longest-established dermal filler brands in the world and continues to be widely used today. It is manufactured by Galderma, a leading global pharmaceutical company, and produced in Sweden. Restylane is approved by the U.S. FDA (United States Food and Drug Administration), South Korea’s regulatory authority, and the European Department for the Quality of Medicines (EDQM).
The manufacturing technology behind Restylane Sweden has continued to evolve. Today, the brand uses two proprietary technologies that allow for customization of the filler’s molecular structure—ensuring the right formulation can be selected for each patient’s skin type and treatment area. These technologies are known as NASHA Technology and OBT Technology

NASHA Technology
Short for Non-Animal Stabilized Hyaluronic Acid Technology, NASHA was first introduced in 1996 and has since been used in more than 70 countries worldwide. It is known for its stability, safety, and low allergenic potential, and has received U.S. FDA and CE mark approvals.
NASHA-based fillers have particle-based gel textures of varying sizes—small, medium, or large—depending on the formulation. This allows the filler to bind and retain water molecules, improving skin hydration without migrating from the injection site. On average, NASHA fillers can last 6 to 12 months, depending on the treatment area and patient.
Fillers in the Restylane NASHA line include:
- Restylane Vital Light
- Restylane Vital
- Restylane Classic
- Restylane Lyft (Perlane Lyft)
Restylane’s NASHA fillers are structured by crosslinking fine HA particles into high-elasticity gels, offering firm support and precision.

OBT Technology
Optimal Balance Technology is a newer generation of Restylane’s filler production technology developed after NASHA. It focuses on delivering flexibility and shape adaptability while still maintaining structural stability. This makes it especially suitable for areas that experience frequent movement, such as the lips or other expressive facial zones.
Fillers in the Restylane OBT line include:
- Restylane Refyne
- Restylane Volyme
- Restylane Defyne
- Restylane Kysse
These OBT-based fillers are commonly chosen by physicians for their ability to maintain shape, softness, and natural facial dynamics across various treatment areas.
How Many Types of Restylane Fillers Are There and What Are They Used For?
The following Restylane Filler products are approved by the Thai FDA for safe use in aesthetic procedures. Each product has unique characteristics suited to specific treatment areas.
- Restylane Perlane Lyft
A firm, high-density filler with lidocaine, ideal for contouring and lifting. It’s commonly used for under-eye hollows, nose augmentation, chin enhancement, jawline definition, or apple cheek volumizing.
With excellent structural stability, it maintains its shape well without spreading.
Longevity: Up to 12 months.

- Restylane Defyne
A medium-soft, resilient filler with lidocaine, designed to correct deep expression lines caused by smiling. It’s ideal for restoring lost volume in deep facial layers, such as the midface, nasolabial folds, marionette lines, and cheekbones, and can also be used under the eyes.
Longevity: Up to 18 months.

- Restylane Vital Light
A skin booster filler with lidocaine and ultra-fine gel particles, designed for subtle, surface-level hydration and skin revitalization.
Perfect for refining under-eye areas, superficial skin layers, lips, and hands.
Longevity: 6–12 months.

- Restylane Volyme
A soft filler with lidocaine that enhances facial volume for a youthful and plump appearance.
Best for treating sunken cheeks, lips, nasolabial folds, and corners of the mouth.
Longevity: Up to 18 months.

- Restylane Refyne
A smooth-textured, flexible filler with lidocaine that targets fine expression lines from smiling and facial movement.
Recommended for lips, nasolabial folds, marionette lines, and mouth corners.
Longevity: Approximately 12 months.

- Restylane Classic
A medium-to-firm filler with lidocaine, using larger gel particles for treating moderate to deep wrinkles in thinner-skinned patients.
Ideal for fine smile lines, glabellar lines (frown lines), and under-eye hollows.
Longevity: Up to 8 months.

- Restylane Vital
A soft-textured, hydrating filler that smooths and rejuvenates the skin, delivering a natural finish.
Commonly used for forehead lines and under-eye areas.
Longevity: Approximately 12 months.

- Restylane Kysse
A specialized filler designed for the lips. With a balance of softness and structure, it defines the lip borders, boosts hydration and volume, and enhances lip color.
Longevity: Up to 12 months.

Restylane offers a wide range of filler types, each with unique properties that can be used in different facial areas to address various concerns, including:
- Under-eye area: Dark circles, hollow eyes, under-eye grooves, wrinkles, or puffiness
- Nasolabial folds: Deep smile lines, visible creases, and sagging in the midface
- Mid-cheek (apple cheek): Sunken cheeks, flat or shallow contours, lack of facial dimension
- Forehead: Flat or sunken forehead, dimples, uneven surface, or deep lines
- Temples: Hollow temples, imbalance in facial proportions
- Lips: Dryness, lip lines, downward corners, undefined shape, or asymmetry
- Chin: Short, recessed, uneven, or dimpled chin; round face lacking contour
- Jawline: Sagging skin, undefined jawline, or lack of V-shape
- Skin revitalization: Dehydrated skin, large pores, rough or uneven skin texture
- Hands: Wrinkled, dry, or aged-looking hands with visible volume loss
The type and amount of filler used should be carefully chosen by an experienced physician, who will select a filler with the appropriate molecular size that matches the treatment area and each patient’s unique skin condition.

How Much Does Restylane Filler Cost?
At V Square Clinic, only FDA-approved Restylane fillers are used—carefully selected for their proven effectiveness in lifting, hydrating, and rejuvenating the skin. Below are the available Restylane options and their recommended applications:
- Restylane Perlane Lyft – 1 CC: 12,000 THB
Suitable for: under-eye hollows, chin, mid-cheek (apple cheek) volume - Restylane Vital Light – 1 CC: 12,000 THB
Suitable for: superficial under-eye skin refinement - Restylane Volyme – 1 CC: 14,000 THB
Suitable for: under-eye area needing volume and structure - Restylane Defyne – 1 CC: 12,900 THB
Suitable for: lips, sunken cheeks, corners of the mouth, nasolabial folds - Restylane Refyne – 1 CC: 14,000 THB
Suitable for: lips, smile lines, corners of the mouth - Restylane Vital – 1 CC: 16,900 THB
Suitable for: under-eye rejuvenation and forehead hydration - Restylane Classic – 1 CC: 9,900 THB
Suitable for: deeper under-eye correction in thin-skinned individuals - Restylane Kysse – 1 CC: 12,900 THB
Suitable for: lip enhancement
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How to Identify a Genuine Restylane Filler?
When receiving a filler injection, it is important not only to choose the right brand and product line suited to the injection area, but also to ensure that the filler is authentic. Counterfeit Restylane fillers do exist in the market. Here are the key signs to help you identify the genuine product:
- The box should have a perforated edge for opening.
- It must contain a Thai FDA registration number and Thai-language product documentation inside the box
- A hologram sticker that reveals the word “VOID” when peeled off
- The lot number must match in two places:
- On the box
- On the syringe
- You can scan the QR Code using the Eztracker app to confirm product authenticity.
- You can also verify the lot number and clinic with the official distributor:
Galderma (Thailand) Co., Ltd.
Tel: 02 023 1800 ext. 402
How to Verify Genuine Restylane Filler
Example of how to verify genuine Restylane Filler — Perlane Lyft model


Note: At V Square Clinic, your filler will always be opened in front of you—both the box and the syringe. After the procedure, you are welcome to take the original packaging home to verify the lot number directly with the official distributor.
Contraindications and Guidelines for Those Considering Restylane Filler
Contraindications
- Never receive filler injections from unlicensed practitioners.
- Do not receive Restylane filler if you are allergic to any of its ingredients.
- Pregnant or breastfeeding women should not receive filler injections.
- If you are taking blood-thinning medications such as aspirin, vitamin E, or fish oil, you should avoid getting fillers.
Guidelines
Before receiving Restylane or any other type of filler, it is important to be well-informed. Key points to consider include:
- Choosing a certified clinic and qualified physician
- Understanding the injection technique used
- Verifying that the filler is authentic
After receiving the injection, proper aftercare is equally important:
- For the first 2–3 nights, sleep with your head elevated above chest level, using at least two pillows. Avoid sleeping on your side to prevent pressure on the face. Use bolsters or pillows to support both sides of your head.
- Avoid washing your face with warm water and steer clear of hot environments like sunlight, stoves, or heat from pans during the first 3 days. Also, avoid excessive facial movements to prevent the filler from shifting.
- Stay hydrated, and avoid touching, rubbing, or applying pressure to the injected area.
- Refrain from alcohol consumption and intense physical activity for at least 48 hours.
- If you wish to get a top-up injection, allow at least 6 months between sessions.
Summary
Restylane is a high-quality, FDA-approved filler recognized globally by medical professionals. It is effective for addressing facial contouring, deep wrinkles, and facial volume loss.
Safety should always be the top priority. Ensure that only authentic Restylane is used, and that the procedure is performed by a licensed, experienced physician who specializes in filler injections.
If you have any further questions, V Square Clinic offers a free consultation with no obligation. You may also contact the clinic via Facebook inbox or LINE for personalized advice.
